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Defining professional boundaries: chemical engineering in the early 20th century. Technology and Culture. Journal of the Society of Chemical Industry. CRC handbook of chemistry and physics , 98th ed. Ng World Scientific Publishing, Singapore, , pp. CRC handbook of chemistry and physics , 98th edn.

Lide, ed. Chan, H. Haynes, editor-in-chief. Credo Reference. Critical Survey of Graphic Novels. Bart H. Beaty and Stephen Weiner, eds. Paramagnetism of polycrystalline gadolinium, terbium, and dysprosium metals, Journal of Applied Physics 32, p. Carter, A. Kaul, R. Laitinen, T. Stability of a vanadium-based Rumble CRC Press, Rumble ed. Astarita, G. The 98th Edition contains several new features including, but not limited to - a major update to the table of isotopes, the first major compilation of high quality data of protein-ligand binding thermodynamics, and an important new collection of NMR data critical for understanding outcomes of organic syntheses.

Plus, twelve lists have been updated such as, the physical properties of organic compounds and the latest experimental values of bond dissociation energies. Building on the new feature first introduced in the 94th edition, four historical figures in science will be honored on the end plates.

For over years, the Handbook has provided property data on chemical compounds now over 20, and all physical particles that have been reported in the literature, carefully reviewed by subject experts. Every year older collections are updated with the latest values and new areas will be added as science progresses.

The material in this new edition compiles cleaning applications into one easy reference that has been fully updated to incorporate new applications and techniques. Taken as a whole, the series forms a unique reference for professionals and academics working in the area of surface contamination and cleaning.

Presents the latest reviewed technical information on precision cleaning applications as written by established experts in the field Provides a single source on the applications of innovative precision cleaning techniques for a wide variety of industries Serves as a guide to the selection of precision cleaning techniques for specific applications. Author : Patrick M. It emphasizes the links between structure, defects, bonding, and properties throughout, and provides an integrated treatment of a wide range of materials, including crystalline, amorphous, organic and nano- materials.

Boxes on synthesis methods, characterization tools, and technological applications distil specific examples and support student understanding of materials and their design. The first six chapters cover the fundamentals of extended solids, while later chapters explore a specific property or class of material, building a coherent framework for students to master core concepts with confidence, and for instructors to easily tailor the coverage to fit their own single semester course.

With mathematical details given only where they strengthen understanding, original figures and over problems for hands-on learning, this accessible textbook is ideal for courses in chemistry and materials science. These electronics will play an increasingly significant role in the future of electronics and will open new product paradigms that conventional semiconductors are not capable of. This is because flexible electronics will allow us to build flexible circuits and devices on a substrate that can be bent, stretched, or folded without losing functionality.

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This book offers the reader a taste of what is possible with FWS electronics and describes how these electronics can provide unique solutions for a wide variety of applications. Furthermore, the book introduces and explains new applications of flexible technology that has opened up the future of FWS electronics. To access this video without a Web connection, users can download a separate version of Strategy 3 that has an embedded Windows Media video file.

Simply save this ZIP file, extract the files to an empty folder on your computer, and open the files from that folder. Content last reviewed December Browse Topics. Topics A-Z. Quality and Disparities Report Latest available findings on quality of and access to health care. CERN is the secretive research lab that has a logo. This scandalous event was widely reported by established mainstream media such as The Times UK.

This is his first absence in circa 30 years. This author questions if Gates is Game Over. Has Gates been replaced with AI? A fitting finale. Independent research is recommended. Gates has publicly argued for the need to reduce global CO2 emissions to zero. This advice from a college dropout who is qualified in nothing is insanity. Plants and trees naturally release CO 2. It is owned by the House of Windsor Crime Family.

He is part of their Committee The execution, imprisonment or natural death of a Committee asset is usually announced decades later. It took decades and billions of dollars in resources to build globally influential brands like Zuckerberg, Soros and Gates. This author merely suspects that nowadays the Bill Gates depopulation vaccine brand was replaced by one or more of: computer generated imagery, Getty Images, holograms, clones and body doubles.

Moving images of Gates look noticeably younger, smoother and digitized compared to a few years ago. Left and center: Moving images. JPEG file image. All images dated Middle: CNN Interview I encourage readers to freely compare online moving and static images of Gates since circa Re: The first image, above left, with the plain pink background and sterile cyborg eyes.

Are these clear liquids loaded with saline psychological placebos or mercury depopulation? All lanes lead to London. These entities are mutually reinforcing. News media bestow wealth and power on fake camera-loving physicists like phony PhD Dr.

His friends publish fake research at fake Medical research universities that do not conduct coursework degrees, such as Rockefeller. Mostly because this concept is repeated in millions of spaces such as fake news, school textbooks and documentaries. This author fearlessly questions whether some, most or all fault lines reported by news and textbooks are fake.

Are mass earthquakes in places like Los Angeles, Iran and Japan caused by underground nuclear tests? Perhaps tunnel creating underground bombs are the cause or part cause.

Merely stating these ideas can cause many, maybe most people to become enraged. Because it challenges their belief system — that humanity can trust those who control narratives. Most corrupt elite science researchers hand-select like- minded business partners as reviewers. Winners who control society pen our fake history books. The same for scientific theory. Maybe at the Gates of Hell. Some want to take things even further, www. Intelligence Says, www.

Karim, www. Ignore the zero. The reasons for this may transpire over time. Celebrities includes famous singers, actors, royals, politicians and other figures such as elite sports players. This tally shows the name of a selected list of celebrity infections as at late April, Names highlighted yellow denotes those who are probably most recognizable among the mainstream.

And I mean the smart people. She has Are you kidding? Bleat, bleat. It is available in the United States by prescription only. Where can I buy It is sold under the brand name Plaquenil and it hydroxychloroquine? It is available in tablets of mg base mg salt. Antimalarial drugs are available in the United States by prescription only.

Medicines should be obtained You should know that the mg base tablet is at a pharmacy before travel rather than in the the same as the mg salt tablet. It is just two destination country. Buying medications abroad different ways of describing the same thing.

This fact sheet provides information about its use In what parts of the world can for the prevention of malaria infection associated with travel. Hydroxychloroquine can only be used in places where chloroquine a related medicine is still effective. There are only a few places left in the world where hydroxychloroquine is still effective including parts of Central America and the Caribbean. CDC keeps track of all the places in the world where malaria transmission occurs and which malaria Who can take hydroxychloroquine?

Who should not take hydroxychloroquine? People with psoriasis should not take hydroxychloroquine. How should I take hydroxychloroquine? Both adults and children should take one dose of Malaria transmission Malaria transmission Malaria transmission is hydroxychloroquine per week starting at least 1 week occurs throughout occurs in some parts not known to occur before traveling to the area where malaria transmission This map shows an approximation of the parts of the world where malaria occurs.

They should take one dose per week while transmission occurs. For more detailed information about the occurrence of malaria transmission in specific countries, please use the interactive Malaria Map Application. The weekly dosage for adults is mg base mg salt. Medication It is caused by a parasite that can should be stored in childproof containers out of the reach of infants and children.

In those diagnosed in the United States each instances, they may not need to take an year almost all in travelers to parts of additional medicine to prevent malaria. Your the world where malaria occurs. How long is it safe to use Will hydroxychloroquine interact hydroxychloroquine? CDC has no limits on the use of Some other drugs can interact with hydroxychloroquine for the prevention of hydroxychloroquine and cause problems. Your malaria. When hydroxychloroquine is used doctor is responsible for evaluating the other at higher doses for many years, a rare eye medicines you are taking to ensure that there condition called retinopathy has occurred.

In some instances, more than five years should get regular medicines can be adjusted to minimize the eye exams. You can also ask your pharmacist to check for drug interactions.

For more information: What are the potential side Check out the CDC malaria website at effects of hydroxychloroquine? The most common adverse reactions with diagnosis or management of reported are stomach pain, nausea, vomiting, suspected cases of malaria should call the and headache. These side effects can often be CDC Malaria Hotline: or lessened by taking hydroxychloroquine with toll-free M-F, 9am-5pm, food. Hydroxychloroquine may also cause eastern time. Emergency consultation after hours, call: All medicines may have some side effects.

If you cannot tolerate your antimalarial drug, see your health care provider; other antimalarial drugs Prevent Malaria are available. Annals of Internal Medicine journalistethics. Paules, MD; Robert W. Eisinger, PhD; Hilary D. Fauci, MD Presidential administrations face any number of unexpected cri- preparation for and response to these threats whenever and ses during their tenure, and global pandemics are among the wherever they emerge.

This article recounts selected outbreaks most challenging. As of January , one of the authors had occurring during this period and highlights lessons that were served under 5 presidents as the director of the National Institute learned that can be applied to the infectious disease threats that of Allergy and Infectious Diseases at the National Institutes of will inevitably be faced in the current presidential administration Health.

During each administration, the government faced unex- and beyond. These experiences underscored the need to optimize This article was published at Annals. I n mid-January , before the U. In addition to terror sonal loyalties to infectious diseases, I cannot conceive attacks, cyberattacks, and natural disasters, outbreaks a need for more infectious-disease experts unless of infectious diseases were presented as a likely threat.

How- One of us Anthony S. Fauci attended that meeting ever, 3 years later, an event occurred that led to the along with other members of the Department of Health stark realization of the real and potential emergence and Human Services to discuss emerging infectious dis- and reemergence of globally important infectious dis- eases. The meeting prompted us to reflect on infec- eases, heralding a trend that would impact and influ- tious disease challenges that have arisen during the 5 ence each of the 5 administrations under which Dr.

Fauci has served as di- Fauci served. During this pe- of Kaposi sarcoma and Pneumocystis pneumonia riod, each administration was confronted with the need among young, previously healthy men who had sex to manage ongoing or established infectious diseases with men in New York City and California was reported as well as new and reemerging infectious disease by the U.

This review highlights selected infectious dis- Centers for Disease Control and Prevention 4, 5. However, in an Annals of Internal Medicine response to such threats. Because current and as-yet article written in and published in 6 , Dr. David O. White, illnesses since the start of the epidemic 7.

To make matters worse for the perception begin dramatically and generate considerable public of the field, Dr. Robert G. It soon became clear that early on.

Upon Dr. This led to advances gan administration took a more active public role in in combination antiretroviral therapy ART that have response to the AIDS outbreak with the issuance transformed the lives of HIV-infected persons. Despite for persons who are diagnosed early and maintain viral this increased effort, these actions were regarded by suppression through combination ART To comple- activists as inadequate for the challenge at hand.

At that time, only a few years after HIV had tious diseases. These infections were Bush underscoring the reality that we live in a global commu- administration. Such research ul- sive culling of poultry by the Hong Kong health author- timately resulted in the introduction of combinations of ities resulted in a temporary end to the outbreak.

However, the The accelerated U. Bush administration, demonstrated the impor- In addition to the emergence of H5N1 avian influ- tance of investing resources in fundamental scientific enza, the Clinton administration was faced with the re- research, including research infrastructure. It also put emergence of West Nile virus, a well-known global in- into sharp focus the critical need to promote direct fectious disease that had never been observed in the communication with affected communities and to gar- Americas.

West Nile virus is a classic example of an old ner the support of political leaders and policymakers in infection that reemerges in a new geographic location. The virus spread rapidly and has since be- sustained clusters of transmission in others. In re- pandemic, which was subsequently found to be caused sponse to this outbreak, the NIAID VRC developed a by a novel coronavirus, resulted in cases and vaccine against West Nile virus and completed a phase deaths before the outbreak ended 28 and had a sub- 1 clinical trial Unfortunately, the vaccine was not stantial negative effect on national and global econo- developed further because of the lack of an industry mies.

The outbreak was successfully controlled with partner. However, it showed the utility of a new vaccine classic public health measures, including early case platform DNA that would undergo advanced develop- identification, patient isolation, and use of personal ment in a subsequent flavivirus outbreak. Bush administration — fore specific countermeasures were developed.

The was faced almost immediately with 2 unprecedented NIAID played a critical role in the research response to domestic public health emergencies. The devastating SARS, developing preclinical vaccine candidates in less terrorist attacks of 11 September were followed than a year by using several novel technologies 29 — within days by detection of anthrax spores in letters to 2 Moreover, with anthrax, 5 of whom died With a substantial this rapid response set the pace for our research re- infusion of new funding, these attacks spurred the sponse to future infectious disease threats.

At the time of infections in both birds and humans Person-to- the anthrax attacks, the NIAID had a modest basic sci- person transmission was suspected in several case clus- ence research program on potential agents of bioter- ters, and although it was inefficient, it caused global rorism In response to the attacks, the institute is- concern that the virus might mutate to adapt itself to sued a series of initiatives and used newly obligated humans and precipitate the next worldwide influenza resources to greatly expand its research portfolio.

In pandemic Congress, responding to the Bush administra- countermeasure development and led to several key tion's request, provided billions of dollars in emer- achievements, including the development of vaccine gency spending to combat the threat of a global influ- candidates against smallpox and Clostridium botuli- enza pandemic. The NIAID, together with its grantees num, antivirals for smallpox, antitoxins for anthrax and and contractors, played a key role in testing vaccine botulinum, and the first clinical Ebola vaccine trials.

At candidates against H5N1 influenza, some of which that time, Ebola was among a group of hemorrhagic were later manufactured and placed in the Strategic fever viruses categorized as CDC category A agents National Stockpile. Bush administration was not fully appreci- increase in infections in sub-Saharan Africa. In , ated until later. Despite the availability of safe and effective thera- and many scientific and public health colleagues be- pies to treat HIV infection, only a fraction of infected lieved that the natural emergence of a virulent patho- persons were receiving treatment.

In response to this gen was an even greater threat Nowhere was this crisis, President George W. This pro- acute respiratory syndrome emerged in and gram had ambitious goals, including preventing 7 H5N1 influenza reemerged in Shortly thereafter, this disease, by then largest global health initiative for a single infectious dis- termed severe acute respiratory syndrome SARS , re- ease that has ever been implemented by any country.

Global examples of emerging and reemerging infectious diseases. Map of the world drawn in the early s and indicating the predominant newly emerging infectious disease at that time HIV. Accumulation of some newly emerging and reemerging infectious diseases since the early s and several that were encountered before then. Some infectious disease outbreaks have had major global health impact, whereas others have appeared as curiosities, with little public health impact. Adapted from reference Bush administration, the Table.

Optimal Response to Emerging Infectious Disease Obama administration — experienced the Outbreaks: Lessons Learned first of several unanticipated infectious disease threats in the early months of its first term.

The H1N1 influenza Global surveillance to detect outbreaks early Transparency and communication in response to outbreaks pandemic, the first influenza pandemic of the 21st cen- Incorporation of infrastructure and capacity building domestically and tury, began in April , just months after the inaugu- internationally in outbreak responses ration. Because seasonal influenza vaccines offered lit- Conduct of basic and clinical research associated with outbreaks in a tle or no protection against this newly emerged virus, coordinated and collaborative manner Involvement of the afflicted communities in policy decisions Congress acted quickly to give the Department of Pursuit and perfection of adaptable platform technologies for Health and Human Services significant additional re- vaccines, diagnostics, and therapeutics sources in anticipation of a second phase of the out- Importance of flexible funding mechanisms break in the fall and winter of Vaccine develop- ment was deemed to be the highest priority, and in early August , as soon as an experimental vaccine lacked public health infrastructure.

By the end of the was available, the NIAID began rapidly enrolling volun- outbreak, Guinea, Liberia, and Sierra Leone reported teers into a clinical trial conducted by its Vaccine and more than 28 cases of Ebola, with 11 deaths Treatment Evaluation Units network.

However, despite The American public reacted to Ebola with a level intense efforts to rapidly develop and test the vaccine, of fear and panic that was disproportionate to the ac- trial results and vaccine supplies were not available un- tual risk to the U.

Although several Ebola- til the late fall and early winter, after the outbreak had infected persons were treated in the United States, all peaked In ad- the inadequacy of our pandemic preparedness capa- dition, most U. As in the example of influenza, history has cessfully treating 2 Ebola-infected persons.

PREVAIL-sponsored studies of sev- scientific disciplines to actively pursue the develop- eral vaccine candidates 42 and the monoclonal anti- ment of such a vaccine a top priority. The H1N1 influenza pandemic ulations. These trials offered important information to was followed in quick succession by outbreaks of chi- guide responses to future Ebola outbreaks. However, in kungunya in the Caribbean in ; Ebola in West Af- the end, infrastructure development; close collabora- rica in ; and, finally, Zika in the southern regions of tion with the host countries; and the implementation of the Americas in Chikungunya virus, an alphavirus classic public health measures, such as safe burial prac- that had previously caused outbreaks in parts of Africa, tices and meticulous contact tracing, brought this his- Asia, Europe, and the Pacific islands, was first noted in toric epidemic to a halt.

It has since caused disease in approximately 2 the Obama administration. Zika virus, an obscure flavi- million persons in the region, with outbreaks ongoing virus believed to have limited clinical significance, was in many countries The NIAID VRC responded detected in Brazil in and was thrust into the public quickly to this threat by developing a novel chikungu- eye when it was linked to an upsurge in microcephaly nya virus—like particle vaccine 40 that is currently in a in Brazil 44 and other countries.

Zika virus has since phase 2 study. This rapid response is a dramatic exam- spread throughout the southern regions of the Ameri- ple of the power of utilizing preexisting platform tech- cas, causing widespread disease.

Puerto Rico and other nologies to expedite vaccine development during an U. In addition, thousands of travel- The reemergence of chikungunya virus was fol- related cases were seen in the continental United lowed by the devastating Ebola crisis in West Africa, States, together with more than locally transmitted which peaked in In addition to microcephaly, Zika virus has pantly in the crowded urban centers of countries that been linked to several other congenital abnormalities Annals.

In response to this outbreak, the NIH rapidly launched a comprehensive research program to better understand the natural history and pathogenesis of References Zika and develop effective countermeasures, such as 1.

Fabian J. White House holds disaster-response exercise with vaccines. The Hill. Burnet M, White DO. Natural History of Infectious Disease. The time 3. Petersdorf RG. The doctors' dilemma. N Engl J Med. Pneumocystis pneumonia—Los extraordinarily short 3 to 4 months 49 , and the vaccine Angeles. Kaposi's sarcoma and Pneu- mocystis pneumonia among homosexual men—New York City and form technologies to permit rapid vaccine develop- California.

Fauci became director of the 6. Fauci AS. The syndrome of Kaposi's sarcoma and opportunistic NIAID, he drew a map of the world for presentation at a infections: an epidemiologically restricted disorder of immunoregu- congressional hearing that showed a single notable lation [Editorial].

Ann Intern Med. Accessed at www. Scheer R. Early indifference to AIDS is blamed for its spread. Los emerged before HIV Figure, bottom. Angeles Times. The current administration will undoubtedly be 9. Isolation of a T-lymphotropic retrovirus from a patient challenged by unanticipated infectious disease out- at risk for acquired immune deficiency syndrome AIDS. Frequent detection and isolation of cytopathic ret- outbreaks Table. Sci- the infectious disease threats that we will inevitably face ence.

Sur- in the current administration and beyond. Public Health Service; Macfarlane Burnet 2 and Petersdorf 3 , we have not seen the end of Experts. NIH Record. We are certain that were. Hellinger FJ. The lifetime cost of treating a person with HIV. Survival with the acquired immunodeficiency syndrome.

Am J Public Health. J Acquir Immune Defic Syndr. Disclosures: Authors have disclosed no conflicts of interest. Characterization of an avian influenza A H5N1 virus isolated from a child with a fatal respiratory illness.

World Health Organization. H5N1 highly pathogenic avian influ- enza: timeline of major events. N Engl. J Med. J Infect Dis. State- ; Birx: U. Centers for Disease Control and Prevention.



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